Health & Wellness

Press Releases

Atlantic Health System Cancer Care First in World to Begin Clinical Trial of Novel Virus-Based Immunotherapy for Late-Stage Melanoma; First Patient Enrolled

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Dr. Eric Whitman Leads Study of Experimental Drug That Uses Cold Virus to Disable Cancer Cells in Patients Who Have Not Responded to Other Treatments

Morristown, NJ Atlantic Health System Cancer Care is the first oncology institution in the world to sign on to, and to enroll the first patient in, a multicenter Phase IIa clinical trial of OBP-301 (Telomelysin®), a virus-based immunotherapy for late-stage melanoma that has not responded to other treatments. 

This leading-edge experimental therapy, which is under development by Japanese biotechnology company Oncolys BioPharma, uses the common cold virus to modify a gene that can selectively replicate in, and destroy, cancer cells. The study protocol was approved by the U.S. Food and Drug Administration (FDA) in June.

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The clinical trial is being led locally by Eric D. Whitman, MD, FACS, medical director of Atlantic Health System Cancer Care and director of the Carol G. Simon Cancer Center’s Atlantic Melanoma Center at Morristown Medical Center and Overlook Medical Center.

“This targeted immunotherapy holds great promise for improving survival rates in patients with unresectable and metastatic melanoma,” said Dr. Whitman.  “We are proud to have been chosen as the first site for this leading edge clinical trial, and happy to be able to offer a wide range of the latest established and experimental treatments to our patients.”

Melanoma, the most serious form of skin cancer, affects more than 50,000 people each year. Although the chances of having melanoma increase with age, the number of cases among young adults is rising every year. Melanoma can have serious health consequences and may even be fatal.

The OBP-301 trial is a multicenter, Phase IIa study to evaluate how melanoma tumors respond to injection of this drug in patients with Stage III and Stage IV melanoma -- that is, to determine how much the drug shrinks or destroys tumors after it is injected into them.  The study, which will also look at potential side effects, is “open label,” meaning that all participants in the study will receive OBP-301. 

OBP-301 is a type of virus known as an adenovirus. Adenoviruses are common in nature and when they multiply in normal human cells they may cause infections that result in symptoms like those of the common cold or the flu.  OBP-301 has been genetically changed from the original virus to reproduce in target cancer cells that are emitting a certain signal. As a result of this reproduction, OBP-301 is believed to burst and kill tumor cells.

Study participants will receive multiple injections into their tumors over a period of several weeks.  Blood tests will be done to evaluate the level of virus in patients’ systems, and for immune response monitoring. Dr. Whitman and colleagues will also evaluate how long it takes to get a response and how long responses last, as well as overall survival and progression-free survival rates.

In preclinical studies, Oncolys demonstrated OBP-301’s anti-tumor activity in various types of cancer cells.  A Phase I clinical trial in the U.S. demonstrated the drug’s safety, and showed that it shrank tumors in a majority of study participants, who had a variety of solid tumors.  Additional studies of the drug have been completed, or are underway, in Japan, Korea and Taiwan.

The Atlantic Melanoma Center, a clinical and research center of excellence, is an internationally-recognized program. The center’s multidisciplinary approach-- combining the expertise of board-certified surgeons, medical oncologists, pathologists, radiation oncologists and nurses – treats all forms of melanoma, including those in the skin, mucous membranes and eyes.  Patients receive the latest medical treatments, and when needed, melanoma surgery is also available. 

For more information on the OBP-301 clinical trial or other studies, please call the Atlantic Melanoma Center at 973-971-7111.  

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Morristown

AtlantiCast

AtlantiCast: Episode 14

On this week’s AtlantiCast, an internationally recognized orthopedic oncologist takes a leadership role at Atlantic Health System, see the newest weapon in the fight against HPV-related cancers, Atlantic Health System leads the Castle Connolly / Inside Jersey Rankings, and much more!

 

I Need to Take Leave from Work Because of a Disability. What are My Rights and Obligations?

According to studies, as many as one in ten persons of working age in the United States have at least one disability.  As a result of a disability or illness, most of us will need to take extended leave during the course of a career.  If you or someone you know suffers from a disability or illness and needs to take time off from work, here are some important things to know:

Leave Can ...

Morris Animal Inn Hosts Live Q&A Session; Wednesday Feb. 28

MORRISTOWN, NJ - Do you have questions about grooming your dog? The Morris Animal Inn is hosting a Live Question and Answer Session on Wednesday February 28 at 11:30am. Tune in to have all your questions answered by Morris Animal Inn's Grooming Manager, Jayanne.

Morris Animal Inn offers:

Bath, brush out, ear cleaning and nail trim package
Haircut to your specifications
Healthy ...

Lend a Hand for Morristown's Annual Spring Clean Up; Saturday April 21

April 18, 2018

MORRISTOWN, NJ - The Town of Morristown will hold its annual Spring Cleanup, this Saturday April 21. Branches and trash that typically accumulate in bushes, parks and along roads and walkways over the winter is more pervasive than usual this year.

The Morristown Beautiful and Morristown Clean Communities are co-sponsoring this year's Spring Clean-Up which will be held on Saturday, ...

Junior League of Morristown hosts Lunch with the Authors

BEDMINSTER NJ - The Junior League of Morristown is proud to present the 17th Annual Lunch with the Authors fundraising event May 4, 2018. The longest running event of its kind in New Jersey includes a panel discussion, book signing, and delicious luncheon featuring nationally acclaimed authors.

Lunch with the Authors has not only been a literary celebration featuring some of the ...

April Events at the Morristown Library

MORRISTOWN, NJ - The Morristown & Morris Township Library has lots of events going on in the month of April. Scroll down to find one for you!

Thursday, April 05

7:00 PM

Three Civil War Generals from Morristown

Disgraced generals and court martials. Bungled orders. Sensational newspaper stories. Political machinations. Insanity and institutions. Idealism and bureaucracy.

Grand Encampment This Weekend at Morristown's Jockey Hollow

April 20, 2018

Morristown, NJ – On Saturday April 21 and Sunday April 22, re-enactors will participate in Jockey Hollows' Grand Encampment. The event focuses on the life and times of soldiers and civilians during the Revolutionary War. 

The re-enactment will take place at Jockey Hollow, 580- 600 Tempe Wick Road Morristown from 11am to 4pm, both days. The events are free and ...

Special Concert in Morristown Features Doolin'; Friday Apr. 20

MORRISTOWN, NJ - The Folk Project will present a special concert featuring Doolin’ on Friday, April 20, 2018 at 7:30 PM. The concert will be held at the Morristown Unitarian Fellowship, 21 Normandy Heights Road in Morristown, NJ. Tickets can be purchased in advance for $20 at www.FolkProject.org or at the door for $25.

Doolin’ is France’s ...

Healthy Plant-Based Eating: A Free Introduction to be Given in Morristown; April 24

MORRISTOWN, NJ -  A free talk on plant based eating will take place at the Morristown & Morris Township Library on Tuesday April 24 at 7pm. Marisa Sweeney, RDN and Co-founder of New Jersey VegFest will lead the discussion which will offer helpful tips for healthy eating.

The presentation will be geared towards people interested in making the jump to veganism as well as those ...

Mennen Sports Arena Welcomes New Skating School Administrator

April 25, 2018

North Atlantic Regional Competitor Whitney Trif Joins The Staff

MORRISTOWN, NJ. The Morris County Park Commission is pleased to announce to Mennen Sports Arena skating staff, Whitney Trif.

Ms. Trif brings an abundance of skating experience as a North Atlantic Regional Competitor, Senior Level in Moves in the Field, and Gold Medalist-Senior Level Freestylist. Previously, she was the Skating ...

Community Invited to Morristown Anniversary Prayer Walk

MORRISTOWN, NJ - Pastors David Smazik and Sidney Williams invite the community to join them for the 175th Bethel Church of Morristown Anniversary Prayer Walk. The Prayer Walk will celebrate the founders of the Bethel African Methodist Episcopal Church as well as the African American soldiers and sailors who are buried in Evergreen Cemetery.

Those interested should meet The Presbyterian ...

Morristown Cat Missing Since Last Week; Help Needed to Find Him

MORRISTOWN, NJ - A cat has been missing from the Morristown area since last week and the owner is asking residents to keep an eye out for him

Jack, is a black and grey short haired tabby cat that is shy but very friendly, stated his owner. He  is an indoor cat, without a collar, that has been missing from the house, in the area of Woodland Avenue And Albert ...

Teens Explore Careers in Aviation at Morristown Airport

April 23, 2018

MORRISTOWN, NJ - On April 18th, a new Aviation Explorer Post was started at Morristown Airport.  The goal of the post is to help young men and women, ages 14-20, learn about careers in aviation. 

At the first meeting, the Explorers toured the airport and discussed which careers the post will focus on at future meetings.  Pilot, air traffic controller, maintenance, and design are ...

The Cora Hartshorn Arboretum is now Accepting Applications to the Cora's Conservation Corps Teen Volunteer Program

The Cora Hartshorn Arboretum is now accepting applications for Cora's Conservation Corps Teen Volunteer Program.

Cora’s Conservation Corps is a service-based program where teens participate in four major activities: environmental education, forest conservation, citizen science, and volunteerism. Through these activities, individuals develop leadership skills, fine-tune public ...

CCM to Air Weekly Television Show

RANDOLPH, NJ – The Alex DeCroce Media Center at County College of Morris (CCM) is now airing a new series of programs titled “Spotlight: Morris County” on Morris Educational Television (METV).

Each 30-minute episode will be aired on METV Channels 40 and 77 on Mondays first at 9 a.m., then at 3 p.m. and again at 9 p.m.

Professor Julian Costa, ...

Improvements Planned for Two Busy 90 Year Old Morris County Bridges, One in Florham Park

April 19, 2018

Florham Park, NJ - Morris County, in coordination with the North Jersey Transportation Planning Authority and New Jersey Department of Transportation, is conducting studies to determine improvements needed for the Columbia Turnpike Bridge in Florham Park and the Valley Road Bridge in Long Hill and Bernards Township, at the Morris and Somerset counties’ ...

Bristol-Myers Squibb Chemist Used Thallium to Poison Husband

April 24, 2018

MONROE, NJ - A local woman who killed her husband using "the poisoner's poison" did not win an appeal yesterday to have her life sentence repealed.

Middlesex County Prosecutor Andrew C. Carey announced that a Monroe Township woman’s 2013 murder conviction was affirmed today by the Superior Court of New Jersey, Appellate Division.

Tianle Li, 48, of Monroe Township ...

Want to avoid gaining weight? Don’t diet!

Researchers aiming to identify lifestyle factors related to weight management followed more than 4,500 young adults (average age 24) for ten years. At the end of the study period, 77% of the men and 72% of the women had gained weight. The lifestyle factors associated with no weight gain among the remaining 23% of the men and 28% of women were regular eating patterns (not skipping meals) and no ...

You Could WIN a New Roof Through No Roof Left Behind

If you live in Sussex, Morris or Warren County and your home needs a new roof, you’re in luck! Jeff Alte Jr. Roofing & Siding will be giving away a free roof to a family in one of these counties through the national No Roof Left Behind program.

Nominations are being accepted through May 31st online only.  Nominate yourself or anyone you know who needs a new roof. Nominees must ...

Retro Review: Johnny Got His Gun by Dalton Trumbo

Retro Review: Johnny Got His Gun by Dalton Trumbo (Citadel Press, 1970)

 

How does a reviewer do justice to a book called “the great American novel”? I first read Johnny Got His Gun during the Viet Nam war, when young people, nationwide, were protesting fighting in a war that was a senseless waste of life; a war in which the United States had no business participating.

'The Sting' shimmers and shakes at Paper Mill

‘The Sting ‘slithers and shakes at Paper Mill Playhouse

By LIZ KEILL

MILLBURN, NJ – In a premiere production of “The Sting,” Harry Connick Jr. commands the Paper Mill Playhouse stage in Millburn.

Based on the sensational Paul Newman/Robert Redford film in 1973, the 1930s plot centers on a con game and gambling, sometimes on a train between New York and ...

Letter to the Editor: Don't Complain. Vote!

April 14, 2018

Don’t Complain; Vote!

It’s no secret that people have strong feelings about what’s happening in our country. It’s also true that much of politics is local. In November, NJ-11th District residents will have the opportunity to choose a new congressional representative who will not only serve as a critical check on the federal level, but also determine how our distract ...

April is STD Awareness Month and Get Yourself Tested Month

April 21, 2018

April is Sexually Transmitted Diseases (STD) Awareness Month, a national campaign to increase awareness about education, treatment, and prevention of STDs.  

STDs are common, affecting 1 in 2 sexually active people during their lifetime - and most people don't know they are infected.  The rate of STDs is increasing, with a 68% increase in bacterial sexually transmitted ...

New Jersey Fashion Companies Capitalize on State Resources to Grow

NJ Business Action Center recently assisted Adore Me and Better Team USA to identify space and financing.

The U.S. apparel market is the largest in the world, valued at over 360 billion dollars. However, the market has been disrupted by the rise of e-commerce, and is moving beyond established locations like NYC’s garment district. 

That said, like every industry, fashion ...

Candidate Statement; Falkner, Gyorfy Announce Bids for Morris Township Committee

April 12, 2018

Dan Falkner and Mark Gyorfy submitted their petitions to run for Morris Township Committee with the endorsements of the Morris County and Morris Township Democratic Committees. Falkner, a Navy veteran and former investment banker, and Gyorfy, a volunteer firefighter and former congressional staffer, intend to bring their public service experience to Morris Township’s governing body to ...

Candidate Statements: John Cesaro and Aura Dunn form Freeholder Ticket

“The Smart, Conservative Choice for Morris County”

Incumbent Cesaro and Mendham Borough resident, Aura Dunn will run together for the Republican Primary on June 5, 2018.

Both candidates hold advanced degrees and have a combined 40 years in public service.  Cesaro, with a law degree from Quinnipiac University and Dunn, a Master of Public Administration from the George ...

Upcoming Events

Wed, April 25

Scherman Hoffman Wildlife Sanctuary, Bernardsville

NJ Audubon: Les Photos de Bernie at the Wayrick ...

Arts & Entertainment Green

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Wed, April 25, 10:00 AM

Morristown

Lucy's Gift features BJWLD Jewelry Designer from ...

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Wed, April 25, 6:00 PM

End Of Elm, Morristown

Whiskey Wednesday

Motor Vehicle Stop Leads to Arrest for Morristown Man

April 24, 2018

4/11: ARREST FOR NARCOTICS: Officers executed a motor-vehicle stop for an equipment violation in Randolph. An investigation led to Sebastian Palacio-Vallejo, age 18, of Wharton, to be charged with Possession of a Controlled Dangerous Substance and Possession of Drug Paraphernalia. He was released with a court date pending.

4/11: ARREST FOR NARCOTICS: Officers executed a motor-vehicle stop for ...

GFWC Woman's Club Participates in Denville Rid Litter Day

April 23, 2018

GFWC Woman’s Club- Denville/Rockaway Participates in Denville PRIDE Rid Litter Day

Close to 400 volunteers came out on a lovely, but windy Saturday to participate in Denville Township’s annual PRIDE, Rid Litter Day.  The timing was perfect, as it also coincides with the 48th anniversary of Earth Day! Earth Day is an annual event created to celebrate the planet's ...